Spontaneous neoplastic lesions in aged Sprague-Dawley rats.
نویسندگان
چکیده
Neoplastic lesions were observed in untreated aged Sprague Dawley (SD) rats throughout their lifespan starting at 5 weeks. Their mean survival times were 89 to 105 weeks of age. The total tumor incidences were 70 to 76.7% and 87 to 95.8% in males and females, respectively. The common neoplasmas were pituitary adenoma and adrenal pheochromocytoma in both sexes, testicular Leydig cell tumor in males and mammary gland tumors, thyroidal C-cell adenoma and uterine stromal polyp in females.
منابع مشابه
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ورودعنوان ژورنال:
- Experimental animals
دوره 50 2 شماره
صفحات -
تاریخ انتشار 2001